He is the head of Sanjeevni Hospital and has spent his entire career as a doctor for this hospital and its patients. He is considered a 'God' in the world of surgery and all interns wait for an opportunity to assist him in the operation theater. Dr Shashank is an idol not only for interns but also other resident doctors of Sanjeevani. Dr Shashank's two daughters Ridhima and Anjali are world to him and all he wants is to see his daughters become competent doctors. Both Riddhima and Anjali come to Sanjieevani to do their internship but get no special treatment for being the daughters of the head of the hospital. Played by Mohnish Behl.
Ridhima is a 21 year old, warm hearted, kind and good-natured girl. Fondly known as Ridz, the single most important thing in her life along with being a good human being is her dream to make her father, Shashank Gupta proud off her achievements in the medical arena. She is intelligent and modern in her outlook to life, and yet respects and represents all the core Indian values. Quick to forgive and forget, at the same time she will not take blatant injustice lying down. Ridhima's weak spot is Anjali, as she allows Anjali to always get the better from her, but that again is not a sign of her weakness. She does so simply because her nature is amenable to everything. Yet, there is one person, an intern like her in Sanjeevani, who manages to awaken the deepest passions of the generally very easy going Ridhima. He irritates her to an extreame point where riddhima looses her temper. How much ever Ridhima tries to ignore Armaan, she cannot. She eventually falls in love with Armaan but her ego drives them apart. Earlier played by Shilpa Anand, and now played by Sukirti Kandpal.
22 year old Armaan represents the new age man; one who is self confident, efficient, cheeky, but yet a kind person at heart. He is also extremely handsome. His professional life is very important to him. He enjoys female company and makes no bones about the fact that he has a weakening knee effect on women. He is used to being the center of female attention and also knows how to sustain that attention when he does receive it. Armaan comes from an affluent family and has never wanted for anything materialistic ever in his life. But beneath the suave and confident exterior lies a focussed doctor, whose sole aim is to outgrow the stigma of being the son of an alcoholic anaesthesiologist. He falls in love with Ridhima, pursuing her relentlessly to fall in love with him too. His life is centered around Ridhima. She makes him laugh, cry, happy, angry or sad. She evokes the most primal emotions in him unlike any other girl he's dated before. He loves her to death. Played by Karan Grover.
Anjali at 22, is Shashank's older daughter and is used to having her way. Extremely beautiful, she is quiet conscious of her looks and not above using them .She is manipulative and conniving. In addition she is also academically intelligent, making her a good doctor in her own right, though she is never a favourite amongst the patients, owing to her to-the-point attitude. Her ultimate aim is to be the head of the organisation Sanjeevani, as it means that she will have power, respectability. And it will declare her as the fitting heir apparent to Shashank's legacy. She will employ all the methods of saam, daam, dand and bhed to get whatever she sets her eyes on. Anjali's manipulative ways are most obvious in the way she handles her sister Ridhima. She however is also protective about Ridhima. Being her granma's favourite she helps set her father up with nurse Padma knowing he needs a life partner. Even though she is hounded by lovetruck Atul, she handles him with maturity and takes care not to be mean to him. Played by Sunaina Gulia.
A lovable character, Atul is the best guy friend a girl can ever have, without ever making him a real boyfriend. He is a good natured, easy going boy, who has become a doctor to fulfill the wish of his dead father, who is part of Sanjeevani alumni. His father worshiped Sanjeevani and Shashank Gupta and he has come to the place of his father's worship to pay his tribute to the man who adopted him. He is always treated like one of the girls when girlie talks are being discussed. When he realizes certain people cannot be changed, he takes mater into his own hands and empties trash, puts cups in trash and carries his own porcelain cup so that the use of Styrofoam cups in Sanjeevani can be reduced. He likes Anjali but Anjali never takes him seriously. Played by Pankit Thakker.
He is a smart, once-ugly new intern from Sanjeevani Amritsar. He was in Armaan's college and was a complete champu. Everyone in the college would have-the-time laugh at him and all the girls would roam around with Armaan, which he hated. He liked one girl-'Sonia'in his college who in turn liked Armaan. He is now in Sanjeevani and is out to trouble Armaan. Though he does have a soft corner too though it isn't evident always. Starts to have feelings for Muskaan. Played by Mayank Anand.
She is the typical non-stop Punjabi chatter box and new intern from Sanjeevani Amritsar. Her family has known Rahul's family for a while and was once engaged to him, but that didn't work out. She hates Rahul a lot and is always out to give him bad words. She loves her 'Dhanu' or her Scooty a lot. She always gets shouting from Dr. Keerti because of her foolish but funny questions. She can make one laugh with her laugh Punjabi jokes and bad words. Played by Drushti Dhami.